Plenary Lecture

Dr. Tomislav Friščić, University of Birmingham

Title: Advancing the Organic Solid State: Mechanochemistry and Carbon-Based Molecular Recognition

Abstract: This lecture will outline our efforts in two distinct areas of organic solid-state chemistry: the design of mechanochemical reactions,[1] and non-conventional approaches to design multi-component solids (cocrystals). We will outline the emergence of “media-free” mechanochemical technologies Resonant Acoustic Mixing (RAM) and SpeedMixing,[2] where the delivery of mechanical energy results from direct oscillation, without externally added agitation media. These approaches, we show, enable design simplicity and scalability difficult to reach using more conventional routes.
In cocrystal design, we will outline the so far poorly recognized potential of halogen bonds for directional assembly of carbon-only systems. Here, we outline a reliable design for the assembly of supramolecular architectures based on non-substituted aromatic hydrocarbons,[3] and a strategy for hierarchical assembly of complex solids by rearranging in space structural subunits pre-assembled from hydrogen-bonded synthons.

[1] Chem. Sci. 2024, 15, 298; [2] Angew. Chem. Int. Ed. 2022, 61, e202206293; [3] Chem. Sci. 2023, 14, 13031.

Time: 11:05 am

Short Talks

Alexandra Dillon, New York University
Ph.D. Candidate - Ward Group

Title: Adaptive guest inclusion in a new aliphatic guanidinium monosulfonate hydrogen-bonded framework

Abstract: During the past three decades, the ability of guanidinium arenesulfonate host frameworks to encapsulate a wide range of guests has been amply demonstrated, with more than 700 inclusion compounds realized. Herein, we report crystalline inclusion compounds based on a new aliphatic host, guanidinium cyclohexanemonosulfonate, which surprisingly exhibits four heretofore unobserved architectures, as described by the projection topologies of the organosulfonate residues above and below hydrogen-bonded guanidinium sulfonate sheets. The aliphatic character of this remarkably simple host combined with access to greater architectural diversity and adaptability, enables the host framework to accommodate a wide range of guests and promises to expand the utility of guanidinium organosulfonate hosts, specifically for structure determination of encapsulated guest molecules.

Time: 11:40 am EST

Lizbeth Rodríguez-Cortés, UNAM
Ph.D. Candidate, Rodriguez-Molina Group

Title: Dual-state emission in organic fluorophores with donor-acceptor architecture (D-A) based on carbazole: synthesis and study of their exceptional conformational emissive states.

Abstract: Organic fluorescent materials have become increasingly popular in the scientific community due to their attractive properties and versatility. Traditionally, fluorescent compounds could only be classified into two groups. The first group includes compounds that display a bright emission in diluted solution but lack emission in the solid state. The second one comprises fluorophores that only exhibit a strong emission when they form aggregates or are in the solid-state. Nevertheless, recent advances in the field have led to the discovery of molecules that can exhibit both emissive properties, making them even more valuable for a wide range of applications, including optoelectronic devices, cell imaging, and sensors. This talk presents the advances in developing organic compounds with donor-acceptor architecture (D-A). It sheds light on the astonishing emissive properties and the different emissive conformations that this kind of molecule could adopt according to the surrounding media, such as in solution or solid-state.

Time: 12:05 pm